»ê°ú LAB

 

AFP

MS(maternal serum)AFP Áõ°¡

15 to 20 weeks¿¡ °Ë»ç

¿Ã¶ó°¡´Â °æ¿ì

  Neural tube defect(žƽŰæ°ü °á¼Õ)

  open spina bifida

  anencephaly

  ventral wall defects(º¹º® °áÇÔ)

  tumors

  dermatologic disorders(ÇǺΰáÇÔ)

  congenital nephrosis(¼Òº¯À¸·Î ¹èÃâÁõ°¡, žƽÅÀå±âÇü)

  aneuploidy(abnormal number of chromosomes within a cell ex.´Ù¿îÁõÈıº trisomy 21)

  õ¹Ì°ñ»À±âÇüÁ¾, ¸²Çª¹°ÁÖ¸Ó´Ï(¹ÚÀÎ¾ç ¿Ü »êÀü ¼±º°°Ë»çÀÇ ÇØ¼®, ´ëÇÑ»êºÎȸÁö)

  ŹÝÀÌ»ó : ŹÝÀÇ À¶¸ð¸·¸Æ°üÁ¾ , ÅÈÁÙÀÇ Ç÷°üÁ¾ , ÀüġŹÝ, À¯ÂøÅ¹Ý, ÅÂ¹Ý °æ»ö(¹ÚÀÎ¾ç ¿Ü »êÀü ¼±º°°Ë»çÀÇ ÇØ¼®, ´ëÇÑ»êºÎȸÁö)

Ç¥Çö : multiples of the median (MoM)·Î Ç¥Çö

ºñÁ¤»ó : 2.0 to 2.5 MoM

ÇØ¼® : MSAFP is >2.5 MoMs is 4.5 percent NTD

      MSAFP level between 2.5 and 2.9 MoMs for NTDs is 1.45 percent

      greater than 7 MoMs, the positive predictive value goes up to 13.5 percent

 

¸ðµÎ uptodate 19.3