»ê°ú LAB
AFP
MS(maternal serum)AFP Áõ°¡

15 to 20 weeks¿¡ °Ë»ç
¿Ã¶ó°¡´Â °æ¿ì
Neural tube defect(žƽŰæ°ü °á¼Õ)
open
spina bifida
anencephaly
ventral
wall defects(º¹º® °áÇÔ)
tumors
dermatologic
disorders(ÇǺΰáÇÔ)
congenital nephrosis(¼Òº¯À¸·Î ¹èÃâÁõ°¡, žƽÅÀå±âÇü)
aneuploidy(abnormal number of chromosomes within a cell ex.´Ù¿îÁõÈıº trisomy 21)
õ¹Ì°ñ»À±âÇüÁ¾, ¸²Çª¹°ÁÖ¸Ó´Ï(¹ÚÀÎ¾ç ¿Ü »êÀü ¼±º°°Ë»çÀÇ ÇØ¼®, ´ëÇÑ»êºÎȸÁö)
ŹÝÀÌ»ó : ŹÝÀÇ À¶¸ð¸·¸Æ°üÁ¾ , ÅÈÁÙÀÇ Ç÷°üÁ¾ , ÀüġŹÝ, À¯ÂøÅ¹Ý, ÅÂ¹Ý °æ»ö(¹ÚÀÎ¾ç ¿Ü »êÀü ¼±º°°Ë»çÀÇ ÇØ¼®, ´ëÇÑ»êºÎȸÁö)
Ç¥Çö : multiples of the median (MoM)·Î Ç¥Çö
ºñÁ¤»ó : 2.0 to 2.5 MoM
ÇØ¼® : MSAFP is >2.5 MoMs is 4.5 percent NTD
MSAFP level between 2.5 and 2.9 MoMs for NTDs is 1.45 percent
greater than 7 MoMs, the positive predictive value goes up to 13.5 percent
¸ðµÎ uptodate 19.3





